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ACE inhibitor angioedema — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyACE inhibitor angioedemaGPhC CRA

A 48-year-old man starts ramipril and returns with swelling of the lips and tongue but no rash. He is speaking in short sentences and feels throat tightness. What is the most appropriate action?

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Correct answer: DCall emergency services for suspected ACE-inhibitor angioedema

ACE inhibitors can cause angioedema, which may threaten the airway and can occur without urticaria. Tongue swelling and throat tightness require emergency assessment. The ACE inhibitor should be stopped and future prescribing reviewed by a clinician.

Reference: BNF; NICE CKS