skip to main content

Morphine in severe CKD — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardRenal and Hepatic ImpairmentMorphine in severe CKDGPhC CRA

A patient recently given morphine is unresponsive with respiratory rate 6/min and pinpoint pupils. A trained responder has take-home naloxone. What is the immediate sequence?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: ECall emergency services, support breathing and repeat naloxone as directed

This is life-threatening opioid toxicity. Emergency services and airway or ventilatory support are priorities; naloxone should be administered according to training and repeated because its action may be shorter than the opioid. Observation remains necessary after apparent response.

Reference: BNF: naloxone hydrochloride: https://bnf.nice.org.uk/drugs/naloxone-hydrochloride/