NSAID risk in heart failure — GPhC CRA MCQ
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Correct answer: A — Topical NSAID or paracetamol with clinical review
Oral NSAIDs can worsen heart failure, blood pressure control and renal function, especially with ACE inhibitor and diuretic therapy. Topical NSAIDs reduce systemic exposure and may be suitable for localised osteoarthritis pain. Persistent or severe pain should be reviewed for broader management.
Reference: BNF; NICE CKS