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Methotrexate weekly dosing error — GPhC CRA MCQ

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HardDispensing and SupplyMethotrexate weekly dosing errorGPhC CRA

A 62-year-old woman taking methotrexate 15 mg once weekly collects a prescription labelled methotrexate 15 mg daily. She says the GP recently increased the dose because her arthritis is active. What is the most appropriate action?

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Correct answer: D — Do not dispense until the dose is clarified urgently

Methotrexate for inflammatory disease is usually taken weekly, and daily dosing is a potentially fatal error. The label conflicts with standard practice and requires urgent clarification before supply. The pharmacist should document the intervention and ensure the patient understands the weekly dosing schedule.

Reference: BNF; MEP