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Adrenal insufficiency sick-day rules — GPhC CRA MCQ

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HardEndocrine TherapeuticsAdrenal insufficiency sick-day rulesGPhC CRA

A 34-year-old woman with adrenal insufficiency collects hydrocortisone 10 mg on waking, 5 mg at lunchtime and 5 mg early evening. She has vomiting and fever and asks whether to skip tablets until she can keep food down. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: BSeek urgent medical help because vomiting may require parenteral steroid

Patients with adrenal insufficiency need sick-day advice because vomiting can prevent absorption and precipitate adrenal crisis. Fever usually requires increased steroid dosing, but inability to retain oral medicines is an emergency. The pharmacist should advise urgent medical assessment and reinforce the importance of carrying steroid emergency information.

Reference: BNF; Society for Endocrinology guidance