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Opioid duplication after discharge — GPhC CRA MCQ

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HardCNS TherapeuticsOpioid duplication after dischargeGPhC CRA

A 66-year-old man taking morphine modified-release 30 mg twice daily is prescribed oxycodone modified-release 20 mg twice daily after hospital discharge. His wife says he still has morphine tablets at home and the discharge letter is unclear. What is the most appropriate action?

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Correct answer: D — Clarify the intended opioid regimen before dispensing

Concurrent long-acting opioid therapy may represent duplication and can cause fatal respiratory depression. Discharge discrepancies with opioids require clarification before supply. The pharmacist should confirm whether this is a switch, ensure breakthrough analgesia is appropriate, and counsel on sedation, constipation and overdose risk.

Reference: BNF; MEP