Valproate pregnancy prevention — GPhC CRA MCQ
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Correct answer: D — Supply if clinically justified and urgently refer for valproate safety review
Abrupt interruption of antiepileptic therapy may cause seizures, so emergency supply may be clinically justified if legal conditions are met. However, valproate has major teratogenic risk and strict pregnancy-prevention requirements, making urgent specialist review essential. The pharmacist should provide safety counselling and document the intervention.
Reference: BNF; MHRA Drug Safety Update