skip to main content

Verapamil and beta-blocker — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardDrug InteractionsVerapamil and beta-blockerGPhC CRA

A patient brings in a prescription for verapamil MR 240 mg daily. Their PMR shows bisoprolol 10 mg daily for atrial fibrillation and they report recent light-headedness. Pulse in the pharmacy is 46 bpm. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Verapamil with bisoprolol may cause bradycardia and heart block

Verapamil and beta-blockers have additive negative effects on heart rate and atrioventricular conduction. The patient already has symptomatic bradycardia, making this a clinically significant interaction rather than a theoretical concern. The prescription should be queried before supply and the patient should be clinically reviewed.

Reference: BNF