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Sulfonylurea hypoglycaemia — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsSulfonylurea hypoglycaemiaGPhC CRA

A 41-year-old woman with type 2 diabetes takes gliclazide 80 mg twice daily. She reports several morning hypos after starting a low-carbohydrate diet and increased exercise; HbA1c was 49 mmol/mol last month. What is the most appropriate action?

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Correct answer: B — Refer to the prescriber for sulfonylurea dose review and provide hypoglycaemia advice

Sulfonylureas can cause hypoglycaemia, particularly with reduced carbohydrate intake or increased exercise. Recurrent morning hypos require prescriber review of dose and timing, plus practical advice on treating hypos and driving safety. Increasing gliclazide would worsen the problem.

Reference: BNF; NICE CKS