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Amlodipine ankle oedema — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsAmlodipine ankle oedemaGPhC CRA

A 62-year-old man is prescribed amlodipine 10 mg daily. He reports bilateral ankle swelling that developed gradually after dose increase; he has no breathlessness, no calf pain, and blood pressure is controlled. What is the most appropriate action?

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Correct answer: D — Discuss likely amlodipine-related oedema with the prescriber rather than adding a diuretic OTC

Ankle oedema is a recognised dose-related adverse effect of dihydropyridine calcium-channel blockers. It is not usually managed effectively with diuretics because it is related to arteriolar dilation rather than fluid overload. The prescriber may consider dose reduction, switching, or combination therapy depending on blood pressure and comorbidities.

Reference: BNF; NICE CKS