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Valproate pregnancy prevention programme — GPhC CRA MCQ

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HardCNS TherapeuticsValproate pregnancy prevention programmeGPhC CRA

A 24-year-old woman taking sodium valproate for epilepsy asks for a repeat supply. She says she is not using contraception because she is not planning pregnancy but could become pregnant. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Check pregnancy prevention programme status and liaise urgently with the prescriber if absent

Valproate has major teratogenic and neurodevelopmental risks and must be managed within the pregnancy prevention requirements for patients who can become pregnant. The patient should not abruptly stop antiepileptic treatment because seizure risk may be serious. The pharmacist should check documentation, counsel, and contact the prescriber or specialist if requirements are not in place.

Reference: MHRA; GPhC valproate guidance; BNF