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H. pylori regimen and warfarin — GPhC CRA MCQ

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HardGI TherapeuticsH. pylori regimen and warfarinGPhC CRA

A 40-year-old man with dyspepsia is prescribed a 7-day H. pylori eradication regimen. He takes warfarin for a mechanical valve and his INR has been unstable recently. What is the most appropriate action?

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Correct answer: C — Contact the prescriber or anticoagulation clinic about interaction and INR plan

H. pylori eradication regimens may include antibiotics that interact with warfarin and destabilise INR. A patient with a mechanical valve is high risk if anticoagulation is changed inappropriately. The pharmacist should liaise with the prescriber or anticoagulation clinic to agree monitoring and management.

Reference: BNF; NICE CKS