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Penicillin allergy — GPhC CRA MCQ

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ModerateInfectionsPenicillin allergyGPhC CRA

A 42-year-old woman asks for advice after being prescribed phenoxymethylpenicillin for tonsillitis. She reports a previous immediate rash, wheeze, and lip swelling after amoxicillin. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Contact the prescriber because a non-penicillin alternative is needed

Wheeze and lip swelling after amoxicillin suggest possible immediate penicillin allergy. Phenoxymethylpenicillin is also a penicillin and should not be supplied without prescriber review. The pharmacist should help arrange an appropriate alternative and ensure the allergy history is recorded.

Reference: BNF; NICE CKS