Montelukast neuropsychiatric effects — GPhC CRA MCQ
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Correct answer: B — Refer promptly to the prescriber to review montelukast and mental health symptoms
Montelukast has been associated with neuropsychiatric reactions, including sleep disturbance, mood changes, and agitation. New mental health symptoms after initiation warrant prompt clinical review and safety-netting. Stopping inhaled corticosteroid would risk asthma deterioration and does not address the suspected adverse effect.
Reference: BNF; MHRA; NICE CKS