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Isotretinoin pregnancy prevention — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyIsotretinoin pregnancy preventionGPhC CRA

A 17-year-old patient brings a private prescription for isotretinoin. The prescription is dated 10 days ago and the patient can become pregnant; documentation shows a negative pregnancy test 9 days ago. What is the most appropriate action?

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Correct answer: E — Check pregnancy prevention requirements and prescription validity before supply

Isotretinoin is highly teratogenic and supply for patients who can become pregnant is subject to strict pregnancy prevention requirements and time limits. The pharmacist must check that the prescription and pregnancy test timing meet the relevant programme requirements before supply. Verbal reassurance alone is not sufficient for safe dispensing.

Reference: MHRA Drug Safety Update; BNF; MEP