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Lithium toxicity — GPhC CRA MCQ

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HardCNS TherapeuticsLithium toxicityGPhC CRA

A 72-year-old man taking lithium carbonate modified-release tablets presents with tremor, vomiting, and new confusion. His daughter says he started ibuprofen for back pain and has been drinking poorly during a diarrhoeal illness. What monitoring is required?

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Correct answer: C — Urgent lithium level, renal function, electrolytes, and medical assessment

This presentation is concerning for lithium toxicity precipitated by dehydration and NSAID use. Urgent lithium concentration, U&Es, renal function, and clinical assessment are required, and further doses should be withheld pending advice. Routine monitoring would be unsafe given neurological and gastrointestinal symptoms.

Reference: BNF; NICE CKS