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ACE inhibitor angioedema — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyACE inhibitor angioedemaGPhC CRA

A patient reports facial swelling and tongue tingling 3 hours after taking the first dose of ramipril. He is breathing comfortably at the counter but the swelling is progressing. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Send for urgent medical assessment and advise no further ramipril

Angioedema can occur with ACE inhibitors and may threaten the airway even if initial symptoms are mild. Progressive facial or tongue swelling requires urgent medical assessment and the ACE inhibitor should not be continued. Switching to another ACE inhibitor would not be appropriate.

Reference: BNF; MHRA; NICE CKS