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Hypertension first-line treatment — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension first-line treatmentGPhC CRA

A 52-year-old man of black African family origin has newly confirmed hypertension. His daytime ABPM average is 158/96 mmHg, eGFR is 82 mL/min/1.73 m2, potassium is 4.3 mmol/L, and he takes no regular medicines. What is the most appropriate action?

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Correct answer: CStart amlodipine and arrange follow-up blood pressure review

Stage 2 hypertension warrants drug treatment as well as lifestyle advice. In an adult of black African or African-Caribbean family origin without type 2 diabetes, a calcium-channel blocker is an appropriate first-line option. ACE inhibitors and ARBs may still be used in specific indications, but ramipril is not the best first choice from the information given.

Reference: NICE CKS; BNF