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ACE inhibitor monitoring — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsACE inhibitor monitoringGPhC CRA

A GP starts lisinopril for a 60-year-old patient with hypertension and type 2 diabetes. Baseline creatinine is 83micromol/L, eGFR 76mL/min/1.73m2 and potassium 4.4mmol/L. The GP asks the pharmacy team what follow-up is needed. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: BCheck renal function and potassium soon after starting and after dose increases.

ACE inhibitors can increase potassium and alter renal function, especially in diabetes or renal disease. Baseline results are acceptable, but monitoring is required after initiation and dose escalation. HbA1c and thyroid function do not assess ACE inhibitor safety.

Reference: BNF; NICE CKS