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Time-critical Parkinson's medicines — GPhC CRA MCQ

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ModerateCNS TherapeuticsTime-critical Parkinson's medicinesGPhC CRA

A 73-year-old man with Parkinson's disease is admitted to a care home for respite. His levodopa/carbidopa is prescribed at 07:00, 11:00, 15:00 and 19:00, but staff plan to give it with the standard 08:00 and 18:00 medicines round. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Explain that levodopa is time-critical and should be administered at the prescribed times.

In Parkinson's disease, delayed or omitted levodopa doses can cause marked deterioration in mobility and swallowing and may precipitate serious complications. Levodopa is a time-critical medicine and should be given at the patient's usual prescribed times. Dopamine antagonists such as prochlorperazine can worsen Parkinsonism.

Reference: BNF; NICE CKS