skip to main content

Metoclopramide extrapyramidal effects — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardGI TherapeuticsMetoclopramide extrapyramidal effectsGPhC CRA

A 59-year-old man takes metoclopramide 10mg three times daily for chronic reflux and has collected repeats for four months. He now reports facial twitching and restlessness. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Contact the prescriber urgently because metoclopramide duration and extrapyramidal effects are concerning.

Metoclopramide is associated with extrapyramidal adverse effects and has restrictions on dose and duration for many indications. New involuntary movements after prolonged use require urgent prescriber review. Adding another dopamine antagonist could worsen extrapyramidal symptoms.

Reference: MHRA Drug Safety Update; BNF