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Hypertension ACE inhibitor initiation — GPhC CRA MCQ

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HardCardiovascular TherapeuticsHypertension ACE inhibitor initiationGPhC CRA

A woman at six weeks’ gestation is taking ramipril for chronic hypertension. The pharmacy is notified of the pregnancy on Monday. Which timetable reflects NICE NG133?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Stop by Wednesday and arrange review to select an alternative antihypertensive

ACE inhibitors and ARBs increase the risk of congenital abnormalities during pregnancy. NICE advises stopping either class preferably within two working days of notification that pregnancy has occurred and offering an alternative antihypertensive. Waiting for a scan prolongs exposure, tapering is unnecessary, and substituting an ARB preserves the same pregnancy-related class risk.

Reference: NICE NG133: https://www.nice.org.uk/guidance/ng133/chapter/recommendations