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H. pylori eradication — GPhC CRA MCQ

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ModerateGI TherapeuticsH. pylori eradicationGPhC CRA

A 49-year-old man has epigastric pain and a positive Helicobacter pylori test. He has NKDA and takes no regular medicines. The GP asks whether the proposed regimen of omeprazole, amoxicillin and clarithromycin is reasonable. What is the most appropriate alternative?

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Correct answer: EConfirm it is an appropriate eradication regimen if local resistance guidance supports it.

H. pylori eradication commonly uses a PPI plus two antibiotics, with choice guided by allergy history and local resistance patterns. Omeprazole, amoxicillin and clarithromycin is a standard option where suitable. Antifungal treatment is not relevant.

Reference: NICE CKS; BNF