A 46-year-old woman taking carbimazole 20mg daily for Graves' disease asks for cold remedies. She has a sore throat, mouth ulcers and temperature

Question

A 46-year-old woman taking carbimazole 20mg daily for Graves' disease asks for cold remedies. She has a sore throat, mouth ulcers and temperature 38.2°C. Her last full blood count was normal two months ago. What monitoring is required?

Accepted Answer

Advise stopping carbimazole and seeking urgent full blood count assessment today.

Answer

Supply amoxicillin under emergency supply.

Answer

Advise doubling carbimazole because infection suggests hyperthyroidism relapse.

Answer

Sell paracetamol and advise continuing carbimazole until the next routine review.

Answer

Recommend ibuprofen and chlorhexidine mouthwash for seven days.

Carbimazole agranulocytosis — GPhC CRA MCQ

A 46-year-old woman taking carbimazole 20mg daily for Graves' disease asks for cold remedies. She has a sore throat, mouth ulcers and temperature 38.2°C. Her last full blood count was normal two months ago. What monitoring is required?