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Propranolol in unstable asthma — GPhC CRA MCQ

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HardRespiratory TherapeuticsPropranolol in unstable asthmaGPhC CRA

A 56-year-old woman with asthma is prescribed propranolol 40mg twice daily for tremor. She uses salbutamol most days and had an ED attendance for wheeze last month. Her peak flow today is 65% of personal best. What is the most important interaction to flag?

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Correct answer: E — Query propranolol with the prescriber because non-selective beta-blockade may worsen asthma.

Non-selective beta-blockers such as propranolol can precipitate bronchospasm and reduce response to beta-2 agonists. This patient has unstable asthma features, including frequent reliever use and recent emergency attendance. The prescription should be queried before supply.

Reference: BNF; NICE CKS