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Hypertension in black African family origin — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension in black African family originGPhC CRA

A 45-year-old man of black African family origin has newly diagnosed hypertension. His ABPM daytime average is 160/100mmHg. He has NKDA, creatinine 68micromol/L, eGFR above 60mL/min/1.73m2, potassium 4.5mmol/L and HbA1c 38mmol/mol. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Recommend starting amlodipine.

In a patient of black African or African-Caribbean family origin without diabetes, a calcium-channel blocker is generally preferred as first-line antihypertensive treatment. The renal function and HbA1c make diabetes or renal impairment less relevant as reasons to choose an ACE inhibitor or ARB first. Amlodipine is therefore the most appropriate initial drug from the options.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment