A 42-year-old woman starts apixaban for VTE. Two days later she develops widespread urticaria and lip swelling after a dose, but no wheeze. She is in

Question

A 42-year-old woman starts apixaban for VTE. Two days later she develops widespread urticaria and lip swelling after a dose, but no wheeze. She is in the pharmacy and feels faint. What is the most appropriate action?

Accepted Answer

Treat as a possible serious hypersensitivity reaction and arrange urgent medical help.

Answer

Switch to aspirin for the rest of the VTE treatment course.

Answer

Report a Yellow Card later but take no immediate action.

Answer

Recommend topical hydrocortisone and continue apixaban.

Answer

Advise taking the next dose with food and monitoring the rash.

Apixaban hypersensitivity — GPhC CRA MCQ

A 42-year-old woman starts apixaban for VTE. Two days later she develops widespread urticaria and lip swelling after a dose, but no wheeze. She is in the pharmacy and feels faint. What is the most appropriate action?