Methotrexate patient counselling — GPhC CRA MCQ
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Correct answer: C — Take methotrexate on the same day each week and report mouth ulcers, bruising or breathlessness.
Methotrexate for rheumatoid arthritis is usually taken once weekly, and daily dosing is a serious safety risk. Patients should know toxicity warning symptoms such as mouth ulcers, unexplained bruising, infection or breathlessness. Folic acid timing should follow the prescriber's directions.
Reference: BNF; MHRA Drug Safety Update