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Methotrexate labelling error — GPhC CRA MCQ

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ModerateDispensing and SupplyMethotrexate labelling errorGPhC CRA

A prescription requests methotrexate 2.5mg tablets, take six tablets once weekly, quantity 24. The label generated by the PMR states 'take six tablets daily'. The patient is waiting and says she usually takes them on Mondays. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CStop the supply, correct the label to weekly dosing and complete an accuracy and clinical check.

Methotrexate dosing errors can be fatal, and the label must match the intended weekly dose before supply. Verbal counselling cannot compensate for an incorrect label on a high-risk medicine. The prescription and PMR should be checked, corrected and counselled clearly.

Reference: BNF; MEP; MHRA Drug Safety Update