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Penicillin allergy assessment — GPhC CRA MCQ

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ModerateInfectionsPenicillin allergy assessmentGPhC CRA

A 50-year-old man prescribed phenoxymethylpenicillin for tonsillitis returns after one dose with a non-itchy maculopapular rash but no breathing symptoms, swelling or mucosal involvement. His record says 'penicillin allergy unknown'. What is the most appropriate action?

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Correct answer: A — Refer to the prescriber to assess allergy history and antibiotic suitability before further doses

Rash after penicillin needs assessment because allergy labels affect future antimicrobial choices, but the severity and timing matter. The pharmacist should clarify symptoms and refer to the prescriber for a decision on continuing or changing therapy. Severe features such as anaphylaxis or mucosal blistering would require urgent care. Removing or broadening allergy labels without assessment is inappropriate.

Reference: BNF; NICE CKS Sore throat