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AF rate control in asthma — GPhC CRA MCQ

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HardCardiovascular TherapeuticsAF rate control in asthmaGPhC CRA

A 67-year-old man with asthma and persistent AF is prescribed propranolol 40mg twice daily for rate control after verapamil caused constipation. He uses salbutamol several times a week and has had two courses of prednisolone this year. What is the most appropriate alternative?

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Correct answer: BDiscuss a more cardioselective beta-blocker or non-beta-blocker option with the prescriber

Non-selective beta-blockers such as propranolol can worsen bronchospasm and antagonise beta-agonists. Asthma severity and recent exacerbations increase the need for caution. Rate-control therapy should be reviewed with the prescriber, considering a more cardioselective option if a beta-blocker is needed or an alternative class. Supplying extra salbutamol does not mitigate the underlying safety issue.

Reference: BNF; NICE CKS Atrial fibrillation