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Isotretinoin pregnancy prevention — GPhC CRA MCQ

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HardAdverse Drug Reactions and SafetyIsotretinoin pregnancy preventionGPhC CRA

A 17-year-old patient is prescribed isotretinoin capsules for severe acne. The prescription is dated 10 days ago and the patient says their pregnancy test was done on the same day. What is the legal classification/requirement?

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Correct answer: C — Check isotretinoin pregnancy-prevention requirements and prescription validity before supply

Isotretinoin is highly teratogenic and subject to strict pregnancy-prevention requirements, including limits on prescription validity and supply quantity for patients who can become pregnant. The pharmacist must check that requirements are met before supply. Verbal reassurance cannot replace the required safeguards. Switching formulation without prescriber involvement is inappropriate.

Reference: BNF; MHRA isotretinoin safety measures