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Reconstituted antibiotic expiry — GPhC CRA MCQ

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ModerateDispensing and SupplyReconstituted antibiotic expiryGPhC CRA

A child is prescribed phenoxymethylpenicillin 250mg/5mL oral solution, 5mL four times daily for 10 days. The product requires reconstitution and has a short shelf-life after preparation. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — The label should include the appropriate expiry after reconstitution and storage instructions

Reconstituted oral antibiotic liquids have product-specific expiry and storage requirements. The dispensing label should include clear storage advice and the expiry after reconstitution. Counselling should reinforce shaking the bottle and completing the prescribed course where appropriate. The manufacturer's unopened expiry no longer applies once reconstituted.

Reference: BNF; product SmPC; MEP