skip to main content

Griseofulvin and contraception — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateDrug InteractionsGriseofulvin and contraceptionGPhC CRA

A woman taking combined hormonal contraception is prescribed griseofulvin for tinea capitis after topical treatment failed. She asks whether contraception is affected. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Griseofulvin can reduce hormonal contraceptive efficacy and extra precautions are needed

Griseofulvin is an enzyme inducer and can reduce the effectiveness of hormonal contraception. The patient needs advice on additional or alternative contraception during treatment and for the recommended period afterwards. Timing with water does not remove enzyme induction. The infection regimen should still be completed if clinically appropriate.

Reference: BNF; Faculty of Sexual & Reproductive Healthcare guidance