Valproate pregnancy prevention — GPhC CRA MCQ
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Correct answer: A — Do not stop valproate suddenly and arrange urgent specialist review about pregnancy risks
Valproate is highly teratogenic and subject to strict pregnancy prevention requirements, but abrupt withdrawal can precipitate seizures. A woman planning pregnancy needs urgent specialist review to consider alternatives and risk minimisation. Pharmacists should ensure the patient understands the Patient Guide and contraception requirements where applicable. The medication should not be stopped or switched at the counter.
Reference: BNF; MHRA Drug Safety Update