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Rivaroxaban missed dose counselling — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsRivaroxaban missed dose counsellingGPhC CRA

A 67-year-old man taking rivaroxaban 20mg once daily with food for AF forgot last night's dose and remembered at breakfast. He has normal renal function and no bleeding. His next dose is due tonight. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: Etake the missed dose now and continue the next dose at the usual time if this follows product guidance

Missed-dose advice for DOACs depends on the specific drug, dose and timing, so product guidance should be followed. For once-daily rivaroxaban, taking the missed dose when remembered on the same day is usually advised, then continuing as normal. Doubling later, substituting aspirin or stopping for several days could increase harm. Taking rivaroxaban with food is important for the 15mg and 20mg doses.

Reference: BNF; SmPC