Biologic DMARD infection risk — GPhC CRA MCQ
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Correct answer: D — refer urgently for assessment and advise withholding the biologic dose until reviewed
Biologic immunosuppressants increase the risk of serious infection. Fever, pleuritic chest pain, tachypnoea and reduced oxygen saturation suggest possible pneumonia requiring urgent assessment. Biologic treatment is commonly withheld during significant infection pending specialist or prescriber advice. Live vaccines and delayed symptomatic treatment are inappropriate in this scenario.
Reference: BNF; NICE CKS: DMARDs