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Amiodarone toxicity monitoring — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyAmiodarone toxicity monitoringGPhC CRA

A patient taking amiodarone develops progressive breathlessness, dry cough, oxygen saturation 93% and unintentional weight loss. What should the pharmacist do?

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Correct answer: BArrange urgent respiratory assessment and immediate amiodarone review

The presentation is compatible with amiodarone pulmonary toxicity, which can progress despite a clear chest examination. Urgent clinical assessment, imaging and specialist-led treatment review are required; routine six-month monitoring does not replace symptom-triggered investigation.

Reference: BNF: amiodarone hydrochloride: https://bnf.nice.org.uk/drugs/amiodarone-hydrochloride/