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Methadone missed doses — GPhC CRA MCQ

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HardCNS TherapeuticsMethadone missed dosesGPhC CRA

A supervised consumption prescription for methadone oral solution states daily instalments. The patient missed three consecutive days and arrives asking for today's dose. He appears mildly tremulous but alert. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Contact the prescriber before supplying methadone

Missing several days of methadone can reduce opioid tolerance and increase overdose risk if the previous dose is resumed. Supervised supply should be managed according to the instalment direction and local substance misuse procedures. The prescriber or service should be contacted before supply. Supplying missed doses together would be unsafe.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment