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Hypothyroidism in pregnancy — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsHypothyroidism in pregnancyGPhC CRA

A 30-year-old woman taking levothyroxine for hypothyroidism has a positive pregnancy test. She is taking 100 micrograms daily and her last TSH three months ago was 3.8 mU/L. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdvise prompt GP or antenatal review because levothyroxine requirements often increase in pregnancy

Pregnancy increases thyroxine requirements in many patients and maternal hypothyroidism can affect pregnancy outcomes. Prompt review and thyroid function monitoring are needed. Levothyroxine should not be stopped. Iron-containing supplements can reduce absorption if taken at the same time, so spacing advice is also relevant.

Reference: BNF; NICE CKS