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Neuroleptic malignant syndrome — GPhC CRA MCQ

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HardCNS TherapeuticsNeuroleptic malignant syndromeGPhC CRA

A 44-year-old man taking haloperidol for psychosis develops fever, severe rigidity, confusion and sweating. His carer asks whether to buy paracetamol and continue the tablets. What is the most appropriate action?

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Correct answer: D — Refer immediately for suspected neuroleptic malignant syndrome

Fever, rigidity, autonomic symptoms and altered mental state in a patient taking an antipsychotic suggest neuroleptic malignant syndrome. This is a medical emergency. Symptomatic treatment and continuation of haloperidol would be unsafe. Immediate referral is required for assessment and supportive management.

Reference: BNF; NICE CKS