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Doxycycline malaria prophylaxis — GPhC CRA MCQ

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ModeratePatient Counselling and Pharmaceutical CareDoxycycline malaria prophylaxisGPhC CRA

A 29-year-old woman is supplied doxycycline for malaria prophylaxis before travel. She also takes a combined oral contraceptive and has a history of oesophagitis. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Take doxycycline with water while upright and use sun protection during treatment

Doxycycline can cause oesophageal irritation, so it should be taken with plenty of water while upright. Photosensitivity is a key counselling point. Antacids and mineral supplements can reduce absorption if taken together. Doxycycline prophylaxis must be taken according to the travel schedule rather than after bites occur.

Reference: BNF; UKHSA malaria guidance