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Sulfonylurea hypoglycaemia — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsSulfonylurea hypoglycaemiaGPhC CRA

A 62-year-old man taking gliclazide 80 mg twice daily has poor appetite after gastroenteritis. He reports sweating and confusion before lunch, and capillary glucose is 3.1 mmol/L. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Treat hypoglycaemia promptly and refer for medication review during reduced intake

Sulfonylureas can cause hypoglycaemia, particularly when oral intake is reduced. The low capillary glucose and symptoms require immediate treatment with fast-acting carbohydrate. Ongoing doses may need review while appetite is poor. Exercise and further sulfonylurea would worsen hypoglycaemia.

Reference: BNF; NICE CKS