Gout flare prophylaxis — GPhC CRA MCQ
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Correct answer: E — Colchicine helps prevent gout flares when urate-lowering therapy is initiated
Starting urate-lowering therapy can precipitate gout flares as urate stores shift. Low-dose colchicine is commonly used as flare prophylaxis during initiation where suitable. Serum urate still needs monitoring and allopurinol titration. The patient should also be counselled about diarrhoea and toxicity risk, especially if renal function changes.
Reference: BNF; NICE CKS