Carbimazole sore throat — GPhC CRA MCQ

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HardEndocrine TherapeuticsCarbimazole sore throatGPhC CRA

A patient taking carbimazole develops sore throat, fever and mouth ulcers. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Stop carbimazole and arrange urgent full blood count

Carbimazole can cause agranulocytosis; fever and sore throat require urgent blood count and drug interruption. In this vignette, "Stop carbimazole and arrange urgent full blood count" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS