GORD step-down — GPhC CRA MCQ
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Correct answer: C — Step down to the lowest effective acid-suppression regimen
Long-term PPI therapy should be reviewed and stepped down where clinically appropriate. In this vignette, "Step down to the lowest effective acid-suppression regimen" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.
Reference: BNF; NICE CKS