ACE inhibitor intolerance — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsACE inhibitor intoleranceGPhC CRA

A patient with hypertension developed persistent cough on ramipril. Their renal function and potassium are normal. What is the most appropriate alternative?

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Correct answer: E — Candesartan

An angiotensin receptor blocker is a suitable alternative when an ACE inhibitor causes troublesome cough. In this vignette, "Candesartan" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS