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High-dose statin safety — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHigh-dose statin safetyGPhC CRA

A patient on atorvastatin 80 mg develops muscle pain after starting a new medicine. The pharmacist is asked which test is most relevant urgently. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Creatine kinase and liver function tests

Muscle symptoms on a statin warrant assessment of creatine kinase, and liver function is also relevant to statin safety. In this vignette, "Creatine kinase and liver function tests" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS