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Alendronic acid administration — GPhC CRA MCQ

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HardMusculoskeletal TherapeuticsAlendronic acid administrationGPhC CRA

A patient plans to take weekly alendronic acid on waking with mineral water, levothyroxine and calcium, then return to bed for 20 minutes. Which single change correctly addresses all important administration errors?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: A — Use plain water; remain upright 30 minutes; delay other tablets 30 minutes

Alendronic acid should be swallowed whole on rising with plain tap water only. The patient must remain sitting or standing and take no food, drink or other oral medicine for at least 30 minutes. Mineral water and calcium reduce absorption, while lying down increases the risk of oesophageal injury.

Reference: NHS: How and when to take alendronic acid: https://www.nhs.uk/medicines/alendronic-acid/how-and-when-to-take-alendronic-acid/