PPI counselling — GPhC CRA MCQ

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EasyGastrointestinal TherapeuticsPPI counsellingGPhC CRA

A patient starts omeprazole for reflux and asks when to take it. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Take it before food, usually before breakfast

PPIs are most effective when taken before food because proton pumps are activated by meals. In this vignette, "Take it before food, usually before breakfast" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS